Current projects
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How TFs/Chromatin remodelers control timing & fate of NSC differentiation into neurons vs oligodendroglia?
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How the dose of chromatin remodelers control normal timing of NSC differentiation vs pathological brain development leading to Autistic Spectrum Disorder (ASD)?
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Assessing the capacity of 2 FDA-approved small molecules to promote (re)myelination in the context of preterm birth brain injury and adult Multiple Sclerosis brain pathologies
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Ascl1 molecular mechanisms in oligodendrogenesis
Present members
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Corentine MARIE, Research Engineer (2013-)
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Morgane PIGACHE, PhD student (2022-)
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Litsa Maria GHAYAD, PhD student (2023-)
- Myriame ABOU MRAD, PhD student (2024-)
Past members
Expertise
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Conditional mutations in mice
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ChIP-seq, RNA-seq, ATAC-seq
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Mouse models of demyelination
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Postnatal electroporation
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CRISPR/Cas9 gene editing
Keywords
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Transcriptional regulation, transcription factors & chromatin remodeling
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Neural stem cell specification and differentiation
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Brain development and neurogenesis
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Oligodendrocyte, myelin and remyelination
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Multiple Sclerosis and myelin diseases
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Autism Spectrum Disorder
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Jean-Baptiste HURE, PhD & Postdoc (2018-2023)
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Lucie PLANTADE, M2 student (2023)
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Natalija IVLJNIN, M2 student (2023)
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Manel BERKEMAL, M2 student (2023)
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Emeric MEROUR, PhD (2017-2021)
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Pierre-Henri HELOU, Master 2 (2021)
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Hatem HMIDAN, PhD (2012-2017)
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Haiyang LU, Master 2 (2016)
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Antoine POTEL, Master 2 (2015)
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Magali FRAH, technical support (2013-2015)
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Theodora BANICA, Master 2 (2014)
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Adrien CLAVAIROLY, PhD (2009-2014)
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Aurélie DELMASURE, Master (2013)
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Elodie M. MARTIN, post-doc (2012-2013)
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Mehdi SAAB, Master 2 (2012)
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Arthur VIADIEU, Master 2 (2011)
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Hessameh HASSANI, post-doc (2008-2012)
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Hiroko NAKATANI, post-doc (2007-2011)
